CO₂-Angioset

ALTERNATIVE CONTRAST MEDIUM SYSTEM FOR IMAGING THE ARTERIAL AND VENOUS VESSELS

Setting of the desired gas volume, adapted to the respective region of examination
Battery and power independent

VALUABLE ALTERNATIVE TO IODINATED CONTRAST MEDIUM.

The CO₂-Angioset is a sterile disposable product for arterial and venous vascular imaging. Medical grade carbon dioxide with a purity ≥ 99.55 vol. % is used as the contrast medium.

Especially in patients with renal insufficiency who are intolerant to iodine-containing CM, the CO₂ -Angioset is recommended as a valuable alternative.¹’³ The CO₂ -Angioset is characterised by its good imaging quality and provides reliable diagnoses, especially in small vessels such as the infrapopliteal segment.³

For the use of the Angioset, a pressure reduction valve from Gloor Medical is required, which is offered in 2 versions:

Version 1: Pressure reduction valve for the gas cylinder connection

Version 2: Pressure reduction valve for the hospital CO₂ wall connection

BENEFITS OF CO₂ ANGIOGRAPHY

THE ONLY 100% BIOCOMPATIBLE CONTRAST AGENT AND THE ALTERNATIVE TO CONVENTIONAL IDOINATED CONTRAST ANGIOGRAPHY

No adverse reactions such as allergy, nephrotoxicity and hepatoxicity
Can be used for patients with an intolerance to iodinated contrast medium
Can be used in combination with iodinated contrast agenst (to reduce side effects of non-ionic contrast agents containing iodine)
Only small-calibre accesses are required (20G, 3F)

GENERAL COMPARISON: CO₂ VERSUS (IODINATED) CONTRAST AGENTS:

Physics	Contrast agent	CO₂
Viscosity	+	–
Flow rate	–	+
Radiopacity	Positive contrast agent	Negative contrast agent
Molecular structure (complexity)	High	Low
Degradation / excretion	Kidneys	Lungs (primarily)
Contraindication	Contrast agent allergy Renal insufficiency Hyper / hypothyroidism	Atrial septal defect Ventricular septal defect Open foramen ovale Respiratory insufficienc Blood vessels above the thoracolumbar junction
Binding capacity of erythrocytes		CO₂ (high) vs O₂ (low)
Henderson-Hasselbach equation		Blood pH deviation with possible changes in the acid-base balance

This comparison represents only a general overview and does not clain to be exhaustive.

For further information, especially about contraindications, please refer to the instructions for use.

This information does not replace the instructions for use – information for medical experts only

CO₂ ANGIOGRAPHY IN PRACTICE – A RELIABLE ALTERNATIVE

FOR A BROAD RANGE OF INTERVENTIONS AND APPLICATIONS – ALSO FOR THE MORE CHALLENGING PATIENTS

Renal insufficiency
Patients with intolerance to iodinated contrast media
Presentations of pathological shunts
Search for sources of haemorrhage
Display of abdominal aortic aneurysms
Hyperthyroidisms
Arteries of the leg

Pelvic arteries
Infrarenal aorta
Visceral arteries
Renal arteries
Hemodialysis shunts
Venous presentation(max. 40 ml pre injection)
Cholangiography(depending on the position)

¹ S3-Leitlinie zur Diagnostik, Therapie und Nachsorge der peripheren arteriellen Verschlusskrankheit 2015
² Radeleff B.: Angiofibel Interventionelle angiographische Diagnostik und Therapie, 2. Auflage Springer 2021
³ Abdulghaffar W.: Role of carbon dioxide angiography in management of below knee arterial lesions, 2012
⁴ Teichgräber et al.: Periphere arterielle Interventionen, Springer 2018
*Im Vergleich zu anderen CO₂-Systemen